Anaphylaxis Statistics
Anaphylaxis is a severe allergic reaction. It is the sudden onset of severe and potentially life-threatening symptoms that occur within minutes to hours of exposure to an allergen.
Severe and Life-Threatening Allergies with References
- 1 to 5 out of every 100 PEOPLE in the U.S. have experienced anaphylaxis (a severe allergic reaction)
- 51% of adults with food allergies have had a severe reaction
- 42% of children with food allergies have had a severe reaction
- 25% of severe allergic reactions in school occur without a prior diagnosis
- $33 BILLION annual direct medical costs in 2024 with CPI-adjusted dollars
- 225 DEATHS per year from anaphylaxis in the U.S.
- Nearly 60% of all anaphylaxis deaths are due to a drug allergy
- 72 DEATHS per year from insect venom allergy









