Hives Caused by Touch or Cold?

Published: December 11, 2024

Revised: March 18th, 2025

This study is no longer enrolling participants.

Join Our Hives Trial!

A person wearing a white shirt is sitting on a couch, scratching a red, irritated patch on their arm. The room appears to be softly lit, with a white blanket draped on the couch.

Are chronic hives triggered by touch or cold temperatures disrupting your life? Consider participating in our research study that is looking EVO756, a new investigational treatment for hives.

Chronic Inducible Urticaria (CindU) refers to chronic hives that can be caused by physical pressure such as scratching or by exposure to cold temperatures. If you or a loved one is effected by Cindu, you may be eligible to participate in the EVO756-CindU research study. Participation will last approximately 10 weeks which includes screening, follow-up and 7 in-person site visits. The investigational treatment (EVO756) will be provided in the form of tablets to be taken twice a day for 4 weeks. No medical insurance required.

Study Criteria

To participate in this study, you must*:

  • Be between 18 and 65 years old,
  • Have a clinical diagnosis of chronic hives (CindU) for at least 3 months,
    • CindU are hives triggered by physical pressures (e.g., touch, scratching) or exposure to cold temperatures
  • Not have itching or hives caused by other skin conditions

*Other eligibility criteria apply. Study drug, visits, tests, and procedures that are done only for the study will be provided at no cost to you. The study staff will tell you about any reimbursement for study-related travel expenses or compensation that may be available.


This study is actively enrolling. Scan the QR code for more information and to see if you qualify!

A black and white QR code on a white background.


Or go to to learn more https://clinago.life/study/evo756-cindu?id=23

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